Hydrochloric Acid → 4-Borono-3-methoxybenzoic acid
反応式
O.[OH-].[Li+].C([O:6][C:7]([C:9]1[CH:14]=[CH:13][C:12]([B:15]([OH:17])[OH:16])=[C:11]([O:18][CH3:19])[CH:10]=1)=[O:8])C.O.Cl>O1CCOCC1>[C:7]([C:9]1[CH:14]=[CH:13][C:12]([B:15]([OH:17])[OH:16])=[C:11]([O:18][CH3:19])[CH:10]=1)([OH:8])=[O:6]参加物
6
実験手順
Lithium hydroxide monohydrate (0.092 g) was added to a mixture of 4-ethoxycarbonyl-2-methoxyphenylboronic acid (0.049 g), water (1 mL) and 1,4-dioxane (1 mL), and the mixture was stirred at room temperature overnight. 2 mol/L hydrochloric acid (1.09 mL) was added to the reaction mixture, and the solvent was evaporated under reduced pressure. The residue was washed with water to afford the title compound (0.035 g).
後処理
- customthe solvent was evaporated under reduced pressure
- washThe residue was washed with water
出典と根拠
- ORDレコード
- ord-4e49a290cc6449e9b2491cdda45e1841
- 出典データセット
- uspto-grants-2008_09
- 特許番号
- US07423185B2
反応ノート
読み込み中…