1-Bromo-3,5-difluorobenzene → 3(3,5-Difluorophenyl)thiophene

HRID 3075

反応式

HRID 3075 の反応式
[F:1][C:2]1[CH:3]=[C:4]([C:10]2[CH:14]=[CH:13][S:12][CH:11]=2)[CH:5]=[C:6]([F:9])[C:7]=1F.BrC1C=C(F)C=C(F)C=1.BrC1C=C(F)C(F)=C(F)C=1>>[F:9][C:6]1[CH:5]=[C:4]([C:10]2[CH:14]=[CH:13][S:12][CH:11]=2)[CH:3]=[C:2]([F:1])[CH:7]=1

参加物

4

反応物 3

HCID 1363131-Bromo-3,5-difluorobenzeneHCID 6114091-Bromo-3,4,5-trifluorobenzeneHCID 232955283-(3,4,5-Trifluorophenyl)thiophene

生成物 1

HCID 227436913(3,5-Difluorophenyl)thiophene

実験手順

The same procedures set forth above in Example (1)(a) for synthesizing 3(3,4,5-trifluorophenyl)thiophene were followed, with the exception that 1-bromo-3,5-difluorobenzene was substituted for 1-bromo-3,4,5-trifluorobenzene as the 1-bromo-substituted fluorobenzene.

出典と根拠

ORDレコード
ord-1353d03acc334b3781453676e9c404d0
出典データセット
uspto-grants-1998_03
特許番号
US05733683

関連ノート

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