化工社化工社 化学情報印刷レポート · 研究参考用
Thiophosgene → HCID 178440816、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thiophosgene | HCID 10040 | — |
| 反応物 | 3-tert-Butylaniline | HCID 79334 | — |
| 反応物 | Sodium Bicarbonate | HCID 516892 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | HCID 178440816 | HCID 178440816 | — |
反応手順
To 3-(tert-butyl)phenylamine in acetone at 0° C. was added sodium bicarbonate (2 eq) and thiophosgene (2 eq). The mixture was brought to ambient temperature and concentrated and partitioned between ethyl acetate and water. The organic layer was dried with sodium bicarbonate and sodium sulfate and concentrated to yield 3-(tert-butyl)benzenisothiocyanate. MS: MH+=192.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07423150B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-5c2f9b6dcb724652b0a751510608c005 |
| 出典メモ | uspto-grants-2008_09 |