5-(Methylsulphonyl)pyridine-3-boronic acid → 4-Fluoro-1-(2-fluoro-5-(5-(methylsulfonyl)pyridin-3-yl)phenyl)-1-(2-(trifluoromethyl)pyridin-4-yl)-1H-isoindol-3-amine

HRID 310507

反応式

[Br:1][c:2]1[cH:3][cH:4][c:5]([F:29])[c:6]([C:8]2([c:19]3[cH:20][c:21]([C:25]([F:26])([F:27])[F:28])[n:22][cH:23][cH:24]3)[N:9]=[C:10]([NH2:18])[c:11]3[c:12]([F:17])[cH:13][cH:14][cH:15][c:16]32)[cH:7]1.[CH3:30][S:31](=[O:32])(=[O:33])[c:34]1[cH:35][c:36]([B:40]([OH:41])[OH:42])[cH:37][n:38][cH:39]1>>[c:2]1(-[c:36]2[cH:35][c:34]([S:31]([CH3:30])(=[O:32])=[O:33])[cH:39][n:38][cH:37]2)[cH:3][cH:4][c:5]([F:29])[c:6]([C:8]2([c:19]3[cH:20][c:21]([C:25]([F:26])([F:27])[F:28])[n:22][cH:23][cH:24]3)[N:9]=[C:10]([NH2:18])[c:11]3[c:12]([F:17])[cH:13][cH:14][cH:15][c:16]32)[cH:7]1