Acetic Acid → 4-Methoxy-2-nitrobenzoic acid
反応式
[N+:1]([C:4]1[CH:11]=[C:10]([O:12][CH3:13])[CH:9]=[CH:8]C=1C#N)([O-:3])=[O:2].[C:14]([OH:17])(=[O:16])[CH3:15].S(=O)(=O)(O)O>O>[N+:1]([C:4]1[CH:11]=[C:10]([O:12][CH3:13])[CH:9]=[CH:8][C:15]=1[C:14]([OH:17])=[O:16])([O-:3])=[O:2]参加物
5
実験手順
A mixture of 2-nitro-4-methoxybenzonitrile (14.0 g, 78.6 mM) in a solution of acetic acid (28 mL), sulfuric acid (28 mL) and water (28 mL) was refluxed for 11 hr, allowed to cool and diluted with water (200 mL). The resulting precipitate which formed was collected, washed with water and dried to give the title benzoic acid (14.2 g, 91.8%) as a yellow crystalline solid; MS(CI): 198 (M+H).
後処理
- temperaturewas refluxed for 11 hr
- temperatureto cool
- customThe resulting precipitate which formed
- customwas collected
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-25ba7dfa0f824982b8c2a5e57de886c1
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05733910
反応ノート
読み込み中…