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HRID 31122作成日：2026年10月26日

(R)-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril → (S)-1-carbomethoxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril

https://huagongshe.com/reaction/31122

反応式

関与物質

役割名称HCID仕込み量
反応物(R)-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyrilHCID 9840862—
反応物(R)-1-carbomethoxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyrilHCID 69194658—
反応物(R)-3-t-butyloxycarbonylamino-3,4-dihydrocarbostyrilHCID 69198597—
生成物(S)-1-carbomethoxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyrilHCID 69196603—

反応手順

The title compound was prepared from (S)-3-t-butyloxycarbonylamino-3,4-dihydrocarbostyril (prepared in Example 5) by the procedures described for the preparation of (R)-1-carbomethoxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril (Example 7) from (R)-3-t-butyloxycarbonylamino-3,4-dihydrocarbostyril. HPLC/MS [M+H]+, 412.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07425550B2
出典データセットuspto-grants-2008_09
ORD IDord-e26c825f1b8d4b71b0c59d1124178a4f
出典メモuspto-grants-2008_09