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HRID 31133作成日：2026年10月26日

(R)-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril → (r)-3-(5-Chloroindole-2-carbonylamino)-1-cyanomethyl-3,4-dihydrocarbostyril

https://huagongshe.com/reaction/31133

反応式

関与物質

役割名称HCID仕込み量
反応物(R)-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyrilHCID 9840862—
反応物(S)-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyrilHCID 44357926—
反応物(S)-3-(5-chloroindole-2-carbonylamino)-1-cyanomethyl-3,4-dihydrocarbostyrilHCID 87730389—
生成物(r)-3-(5-Chloroindole-2-carbonylamino)-1-cyanomethyl-3,4-dihydrocarbostyrilHCID 87730651—

反応手順

The title compound was prepared from (R)-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril (Example 3) by the procedures described for the preparation of (S)-3-(5-chloroindole-2-carbonylamino)-1-cyanomethyl-3,4-dihydrocarbostyril (Example 17) from (S)-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril. HPLC/MS [M+H]+, 379.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07425550B2
出典データセットuspto-grants-2008_09
ORD IDord-c589ae9a6fe54ae2b8d8bd6faa1bb75d
出典メモuspto-grants-2008_09