Imidazole → 7-{4-[2-(1H-1-imidazolyl)ethyl]cyclohexyl}-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

反応式

[CH3:44][N:45]([CH3:46])[CH:47]=[O:48].[CH3:6][S:7]([O:8][CH2:11][CH2:12][CH:13]1[CH2:14][CH2:15][CH:16]([n:19]2[cH:20][c:21](-[c:29]3[cH:30][cH:31][c:32]([O:35][c:36]4[cH:37][cH:38][cH:39][cH:40][cH:41]4)[cH:33][cH:34]3)[c:22]3[c:23]2[n:24][cH:25][n:26][c:27]3[NH2:28])[CH2:17][CH2:18]1)(=[O:9])=[O:10].[H-:42].[Na+:43].[nH:1]1[cH:2][n:3][cH:4][cH:5]1>>[n:1]1([CH2:11][CH2:12][CH:13]2[CH2:14][CH2:15][CH:16]([n:19]3[cH:20][c:21](-[c:29]4[cH:30][cH:31][c:32]([O:35][c:36]5[cH:37][cH:38][cH:39][cH:40][cH:41]5)[cH:33][cH:34]4)[c:22]4[c:23]3[n:24][cH:25][n:26][c:27]4[NH2:28])[CH2:17][CH2:18]2)[cH:2][n:3][cH:4][cH:5]1