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Diethyl Sulfate → 2-Bromophenetole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diethyl Sulfate | HCID 6163 | — |
| 反応物 | 2-Bromophenol | HCID 7244 | — |
| 溶媒 | Sodium Hydroxide | HCID 14798 | — |
| 生成物 | 2-Bromophenetole | HCID 68500 | — |
反応手順
A mixture of 17.5 g of 2-bromophenol, 66 ml of diethyl sulphate and 170 ml of 10% NaOH solution is refluxed for 2 hours. After cooling the reaction mixture to RT, it is extracted with EtOAc, the organic phase is washed with 2N NaOH solution and dried over Na2SO4, and the solvent is evaporated off under vacuum. 19.6 g of the expected product are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07425566B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-7430bb1eac354422a753a5f7420cbe7a |
| 出典メモ | uspto-grants-2008_09 |