化工社化工社 化学情報印刷レポート · 研究参考用
N-cyclopropyl-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide → 6-Methyl-4'-(5-morpholin-4-ylmethyl-[1,3,4]oxadiazol-2-yl)-biphenyl-3-carboxylic acid cyclopropylamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-cyclopropyl-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide | HCID 21914577 | — |
| 反応物 | 4-[5-(4-Iodophenyl)-[1,3,4]oxadiazol-2-ylmethyl]-morpholine | HCID 69317784 | — |
| 生成物 | 6-Methyl-4'-(5-morpholin-4-ylmethyl-[1,3,4]oxadiazol-2-yl)-biphenyl-3-carboxylic acid cyclopropylamide | HCID 10387295 | — |
反応手順
Example 14 was prepared from 4-[5-(4-iodophenyl)-[1,3,4]oxadiazol-2-ylmethyl]-morpholine (Intermediate 10) and N-cyclopropyl-4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]-dioxaborolan-2-yl)benzamide (Intermediate 17).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07425555B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-33175f4281f24e8abc87ddb390bc80d6 |
| 出典メモ | uspto-grants-2008_09 |