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Isopropanol → 6-Methyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)-biphenyl-3-carboxylic acid (3-methoxy-phenyl)-amide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Isopropanol | HCID 3776 | — |
| 反応物 | 2-(4-Iodophenyl)-5-methyl-[1,3,4]oxadiazole | HCID 676569 | — |
| 反応物 | 6,2'-Dimethyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-3-carboxylic acid (3-morpholin-4-yl-phenyl)amide | HCID 58629800 | — |
| 生成物 | 6-Methyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)-biphenyl-3-carboxylic acid (3-methoxy-phenyl)-amide | HCID 10408626 | — |
反応手順
Example 37 was prepared using 2-(4iodophenyl)-5-methyl-[1,3,4]oxadiazole (Intermediate 15) and N-3-methoxy-phenyl)-4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide (Intermediate 6) with propan-2-ol as the solvent.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07425555B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-f0dfb40fb3f24125ae27a4c2b4130b0b |
| 出典メモ | uspto-grants-2008_09 |