2-(6-Bromopyridin-2-yl)-2-methylpropanenitrile → 2-{[6-(1-Cyano-1-methylethyl)pyridin-2-yl]amino}-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide
反応式
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]([C:8]([C:9]#[N:10])([CH3:11])[CH3:12])[n:7]1.[NH2:13][c:14]1[s:15][c:16](-[c:22]2[c:23]([F:33])[cH:24][c:25]([C:29]([CH3:30])([CH3:31])[OH:32])[cH:26][c:27]2[F:28])[cH:17][c:18]1[C:19](=[O:20])[NH2:21]>>[c:2]1([NH:13][c:14]2[s:15][c:16](-[c:22]3[c:23]([F:33])[cH:24][c:25]([C:29]([CH3:30])([CH3:31])[OH:32])[cH:26][c:27]3[F:28])[cH:17][c:18]2[C:19](=[O:20])[NH2:21])[cH:3][cH:4][cH:5][c:6]([C:8]([C:9]#[N:10])([CH3:11])[CH3:12])[n:7]1参加物
3
出典と根拠
- ORDレコード
- ord-187df46aaa5c492f8c0f13ede32d76c3
- 出典データセット
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
反応ノート
読み込み中…