Carbon Disulfide → HCID 178505474、化合物

HRID 31679

反応式

HRID 31679 の反応式
[NH2:1][C:2]1[CH:3]=[C:4]([F:9])[CH:5]=[CH:6][C:7]=1[NH2:8].[C:10](=S)=[S:11]>CO>[F:9][C:4]1[CH:5]=[CH:6][C:7]2[NH:8][C:10]([SH:11])=[N:1][C:2]=2[CH:3]=1

参加物

4

反応物 2

HCID 6348Carbon DisulfideHCID 1645844-Fluorobenzene-1,2-diamine

生成物 1

HCID 178505474HCID 178505474、化合物収率 98.2%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

A mixture of 3,4-diamino-1-fluorobenzene (10 g, 79.3 mmol), carbon disulfide (70 ml, 1164 mmol), and methanol (100 ml) was stirred at room temperature for 86 hours and 50 minutes. After the reaction mixture was concentrated, the residue was suspended in hexane. The resultant precipitate was collected by filtration and washed with hexane to obtain the title compound (13.1 g, yield: 98.2%) as a brown solid.

後処理

  1. concentrationAfter the reaction mixture was concentrated
  2. filtrationThe resultant precipitate was collected by filtration
  3. washwashed with hexane

出典と根拠

ORDレコード
ord-31450aeabdf747aeb96b5606f43929aa
出典データセット
uspto-grants-2008_09
特許番号
US07425634B2

関連ノート

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