1,4-Benzodioxane-2-methanol → 2-(((4-(2,3-Dihydro-1,4-benzodioxin-2-ylmethoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt

関与物質

役割	名称	HCID	仕込み量
反応物	1,4-Benzodioxane-2-methanol	HCID 19314	—
反応物	2-(((3-Methyl-4-(2-(2-propyl-1,3-dioxan-2-yl)ethoxy)pyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt	HCID 66776694	—
生成物	2-(((4-(2,3-Dihydro-1,4-benzodioxin-2-ylmethoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt	HCID 66776275	3%

反応手順

The same procedure as in the steps (8c) to (8g) of Example 8 was repeated using 2-hydroxymethyl-1,4-benzodioxane to obtain the title compound (141 mg, total yield: 3%) as a white solid.

情報源と証拠

DOI	10.6084/m9.figshare.5104873.v1
特許番号	US07425634B2
出典データセット	uspto-grants-2008_09
ORD ID	ord-461e9c9428284904b53b2453491a6152
出典メモ	uspto-grants-2008_09