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HRID 31877作成日：2026年10月26日

4-(Trifluoromethyl)benzoyl chloride → {5-Imidazol-2-yl-4-[4-(trifluoromethyl)phenyl]pyrimidin-2-yl}(2-{[5-(trifluoro-methyl)(2-pyridyl)]amino}ethyl)amine

https://huagongshe.com/reaction/31877

反応式

関与物質

役割名称HCID仕込み量
反応物4-(Trifluoromethyl)benzoyl chlorideHCID 67607—
反応物2-Chloro-5-(trifluoromethyl)pyridineHCID 92342—
反応物Chir-98023HCID 9847557—
生成物{5-Imidazol-2-yl-4-[4-(trifluoromethyl)phenyl]pyrimidin-2-yl}(2-{[5-(trifluoro-methyl)(2-pyridyl)]amino}ethyl)amineHCID 22142530—

反応手順

{5-imidazol-2-yl-4-[4-(trifluoromethyl)phenyl]pyrimidin-2-yl}(2-{[5-(trifluoromethyl)(2-pyridyl)]amino}ethyl)amine was prepared from 4-(trifluoromethyl)benzoyl chloride and 2-chloro-5-(trifluoromethyl)pyridine using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07425557B2
出典データセットuspto-grants-2008_09
ORD IDord-faa1fe6c4e8844d0977ae26a7d897d97
出典メモuspto-grants-2008_09