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HRID 31878作成日：2026年10月26日

1,2-Dimethylimidazole → 6-[(2-{[4-(2,4-Dichlorophenyl)-5-(1-methylimidazol-2-yl)pyrimidin-2-yl]amino}-ethyl)amino]pyridine-3-carbonitrile

https://huagongshe.com/reaction/31878

反応式

関与物質

役割名称HCID仕込み量
反応物1,2-DimethylimidazoleHCID 15617—
反応物6-Chloro-3-pyridinecarbonitrileHCID 5152094—
反応物Chir-98023HCID 9847557—
生成物6-[(2-{[4-(2,4-Dichlorophenyl)-5-(1-methylimidazol-2-yl)pyrimidin-2-yl]amino}-ethyl)amino]pyridine-3-carbonitrileHCID 22142822—

反応手順

6-[(2-{[4-(2,4-dichlorophenyl)-5-(1-methylimidazol-2-yl)pyrimidin-2-yl]amino}-ethyl)amino]pyridine-3-carbonitrile was prepared from 1,2-dimethylimidazole and 2-chloro-5-(cyano)pyridine using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07425557B2
出典データセットuspto-grants-2008_09
ORD IDord-3108dd7de06347139d26d03e283095de
出典メモuspto-grants-2008_09