4-Fluoro-2-(trifluoromethyl)benzoyl chloride → {4-[4-Fluoro-2-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}{2-[(5-nitro(2-pyridyl))amino]ethyl}amine

HRID 31884

反応式

HRID 31884 の反応式
[F:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=O)=[C:4]([C:11]([F:14])([F:13])[F:12])[CH:3]=1.ClC1C=C(Cl)C=CC=1C1[C:28]([C:29]2[NH:30][CH:31]=[CH:32][N:33]=2)=[CH:27][N:26]=[C:25]([NH:34][CH2:35][CH2:36][NH:37][C:38]2[CH:43]=[CH:42][C:41]([N+:44]([O-:46])=[O:45])=[CH:40][N:39]=2)[N:24]=1>>[F:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]2[C:28]([C:29]3[NH:33][CH:32]=[CH:31][N:30]=3)=[CH:27][N:26]=[C:25]([NH:34][CH2:35][CH2:36][NH:37][C:38]3[CH:43]=[CH:42][C:41]([N+:44]([O-:46])=[O:45])=[CH:40][N:39]=3)[N:24]=2)=[C:4]([C:11]([F:14])([F:13])[F:12])[CH:3]=1

参加物

3

反応物 2

HCID 6056804-Fluoro-2-(trifluoromethyl)benzoyl chlorideHCID 9847557Chir-98023

生成物 1

HCID 22142951{4-[4-Fluoro-2-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}{2-[(5-nitro(2-pyridyl))amino]ethyl}amine

実験手順

{4-[4-fluoro-2-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}{2-[(5-nitro(2-pyridyl))amino]ethyl}amine was prepared from 4-fluoro-2-(trifluoromethyl)benzoyl chloride using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.

出典と根拠

ORDレコード
ord-c68b266a08b440bbaf80b61c807e58ec
出典データセット
uspto-grants-2008_09
特許番号
US07425557B2

関連ノート

読み込み中…