反応式
[F:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=O)=[C:4]([C:11]([F:14])([F:13])[F:12])[CH:3]=1.Cl[C:16]1[CH:21]=[CH:20][C:19]([C:22]#[N:23])=[CH:18][N:17]=1.ClC1C=C(Cl)C=CC=1C1[C:37]([C:38]2[NH:39][CH:40]=[CH:41][N:42]=2)=[CH:36][N:35]=[C:34]([NH:43][CH2:44][CH2:45][NH:46]C2C=CC([N+]([O-])=O)=CN=2)[N:33]=1>>[F:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]2[C:37]([C:38]3[NH:39][CH:40]=[CH:41][N:42]=3)=[CH:36][N:35]=[C:34]([NH:43][CH2:44][CH2:45][NH:46][C:16]3[N:17]=[CH:18][C:19]([C:22]#[N:23])=[CH:20][CH:21]=3)[N:33]=2)=[C:4]([C:11]([F:14])([F:13])[F:12])[CH:3]=1参加物
4
実験手順
6-{[2-({4-[4-fluoro-2-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}amino)ethyl]amino}pyridine-3-carbonitrile was prepared from 4-fluoro-2-(trifluoromethyl)benzoyl chloride and 2-chloro-5-(cyano)pyridine using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.
出典と根拠
- ORDレコード
- ord-b7597be2bc6c4cdcbeb2cd08a6838035
- 出典データセット
- uspto-grants-2008_09
- 特許番号
- US07425557B2
関連ノート
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