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HRID 31891作成日：2026年10月26日

2-Chloro-5-(trifluoromethyl)pyridine → {4-[4-Fluoro-2-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}(2-{[5-(trifluoromethyl)(2-pyridyl)]amino}ethyl)amine

https://huagongshe.com/reaction/31891

反応式

関与物質

役割名称HCID仕込み量
反応物2-Chloro-5-(trifluoromethyl)pyridineHCID 92342—
反応物4-Fluoro-2-(trifluoromethyl)benzoyl chlorideHCID 605680—
反応物Chir-98023HCID 9847557—
生成物{4-[4-Fluoro-2-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}(2-{[5-(trifluoromethyl)(2-pyridyl)]amino}ethyl)amineHCID 22142758—

反応手順

{4-[4-fluoro-2-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}(2-{[5-(trifluoromethyl)(2-pyridyl)]amino}ethyl)amine was prepared from 4-fluoro-2-(trifluoromethyl)benzoyl chloride and 2-chloro-5-(trifluoromethyl)pyridine using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07425557B2
出典データセットuspto-grants-2008_09
ORD IDord-5ba8b4976bb840ecae19d4a9ed2ef649
出典メモuspto-grants-2008_09