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HRID 31897作成日：2026年10月26日

2-Fluoro-4-(trifluoromethyl)benzoyl chloride → 6-{[2-({4-[2-Fluoro-4-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}amino)ethyl]amino}pyridine-3-carbonitrile

https://huagongshe.com/reaction/31897

反応式

関与物質

役割名称HCID仕込み量
反応物2-Fluoro-4-(trifluoromethyl)benzoyl chlorideHCID 145580—
反応物6-Chloro-3-pyridinecarbonitrileHCID 5152094—
反応物Chir-98023HCID 9847557—
生成物6-{[2-({4-[2-Fluoro-4-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}amino)ethyl]amino}pyridine-3-carbonitrileHCID 22143005—

反応手順

6-{[2-({4-[2-fluoro-4-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}amino)ethyl]amino}pyridine-3-carbonitrile was prepared from 2-fluoro-4-(trifluoromethyl)benzoyl chloride and 2-chloro-5-(cyano)pyridine using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07425557B2
出典データセットuspto-grants-2008_09
ORD IDord-ff3164a08e7c405abae323144533f98f
出典メモuspto-grants-2008_09