Benzaldehyde → Benzaldehyde 4-(4-chloro-alpha-cyanobenzyl)-3,5-dichlorophenyl hydrazone

反応式

[Cl:1][C:2]1[CH:20]=[CH:19][C:5]([CH:6]([C:9]2[C:14]([Cl:15])=[CH:13][C:12]([NH:16][NH2:17])=[CH:11][C:10]=2[Cl:18])[C:7]#[N:8])=[CH:4][CH:3]=1.[CH:21](=O)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1.S([O-])([O-])(=O)=O.[Mg+2]>C(OC(=O)C)C>[Cl:1][C:2]1[CH:20]=[CH:19][C:5]([CH:6]([C:9]2[C:10]([Cl:18])=[CH:11][C:12]([NH:16][N:17]=[CH:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)=[CH:13][C:14]=2[Cl:15])[C:7]#[N:8])=[CH:4][CH:3]=1

参加物

実験手順

In 30 ml of acetic acid ethyl ester was dissolved 3.26 g of 4-(4-chloro-α-cyanobenzyl)-3,5-dichlorophenyl hydrazine. To the solution was added equimolar benzaldehyde and three times as much mol. of anhydrous magnesium sulfate, then the reaction was allowed to proceed for one hour at room temperature. After completion of the reaction, insolubles were removed, and the solution was concentrated, which was recrystallized from acetonitrile to afford 3.3 g of the titled compound as colorless crystals, m.p.162-163° C.