化工社化工社 化学情報印刷レポート · 研究参考用
1,3-Dichloroacetone → 2-(4-Benzyloxy-phenyl)-4-chloromethyl-oxazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,3-Dichloroacetone | HCID 10793 | — |
| 反応物 | 4-Benzyloxybenzamide | HCID 2726431 | — |
| 生成物 | 2-(4-Benzyloxy-phenyl)-4-chloromethyl-oxazole | HCID 22009845 | 33% |
反応手順
In substantially the same manner as in Reference Example 31, 4-benzyloxybenzamide was allowed to react with 1,3-dichloroacetone to give 2-(4-benzyloxyphenyl)-4-chloromethyloxazole. The yield was 33%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 119-120° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06211215B1 |
| 出典データセット | uspto-grants-2001_04 |
| ORD ID | ord-c866ceb1ade34cdda156129c141a786c |
| 出典メモ | uspto-grants-2001_04 |