化工社化工社 化学情報印刷レポート · 研究参考用
1,3-Dichloroacetone → 4-[4-(Chloromethyl)-1,3-oxazol-2-yl]benzonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,3-Dichloroacetone | HCID 10793 | — |
| 反応物 | p-Cyanobenzamide | HCID 76427 | — |
| 生成物 | 4-[4-(Chloromethyl)-1,3-oxazol-2-yl]benzonitrile | HCID 22009640 | 41% |
反応手順
In substantially the same manner as in Reference Example 31, 4-cyanobenzamide was allowed to react with 1,3-dichloroacetone to give 4-chloromethyl-2-(4-cyanophenyl)oxazole. The yield was 41%. Recrystallization form ethyl acetate-hexane gave colorless prisms, mp 134-135° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06211215B1 |
| 出典データセット | uspto-grants-2001_04 |
| ORD ID | ord-8f68c7735093494694dce59073b3aa24 |
| 出典メモ | uspto-grants-2001_04 |