4,5-Diphenylimidazole → HCID 22009650、化合物

HRID 322367

反応式

HRID 322367 の反応式
CS(O[CH2:6][CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][C:17]2[N:18]=[C:19](/[CH:22]=[CH:23]/[C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[O:20][CH:21]=2)=[CH:11][CH:10]=1)(=O)=O.[C:30]1([C:36]2[N:37]=[CH:38][NH:39][C:40]=2[C:41]2[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=2)[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1>>[C:30]1([C:36]2[N:37]=[CH:38][N:39]([CH2:6][CH2:7][CH2:8][C:9]3[CH:10]=[CH:11][C:12]([O:15][CH2:16][C:17]4[N:18]=[C:19](/[CH:22]=[CH:23]/[C:24]5[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=5)[O:20][CH:21]=4)=[CH:13][CH:14]=3)[C:40]=2[C:41]2[CH:42]=[CH:43][CH:44]=[CH:45][CH:46]=2)[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1

参加物

3

反応物 2

HCID 695884,5-DiphenylimidazoleHCID 155216743-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl methanesulfonate

生成物 1

HCID 22009650HCID 22009650、化合物収率 53%

実験手順

In substantially the same manner as in Working Example 25, 3-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl methanesulfonate was allowed to react with 4,5-diphenylimidazole to give 4-[4-[3-(4,5-diphenyl-1-imidazolyl)propyl]phenoxymethyl]-2-[(E)-2-phenylethenyl]oxazole. The yield was 53%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 137-138° C.

出典と根拠

ORDレコード
ord-cc6b7c4992ea4fd9956d53d48e82b2d4
出典データセット
uspto-grants-2001_04
特許番号
US06211215B1

関連ノート

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