反応式
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:12]=[CH:11][N:10]=[CH:9]2)=[CH:4][CH:3]=1.Cl[CH2:14][C:15]1[N:16]=[C:17](/[CH:20]=[CH:21]/[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[O:18][CH:19]=1>>[N:8]1([C:5]2[CH:4]=[CH:3][C:2]([O:1][CH2:14][C:15]3[N:16]=[C:17](/[CH:20]=[CH:21]/[C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=4)[O:18][CH:19]=3)=[CH:7][CH:6]=2)[CH:12]=[CH:11][N:10]=[CH:9]1参加物
3
実験手順
In substantially the same manner as in Working Example 37, 1-(4-hydroxyphenyl)imidazole was allowed to react with 4-chloromethyl-2-[(E)-2-phenylethenyl]oxazole to give 4-[4-(1-imidazolyl)phenoxymethyl]-2-[(E)-2-phenylethenyl]oxazole. The yield was 68%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 160-162° C.
出典と根拠
- ORDレコード
- ord-a2539587f2ab45ccb443b3bde9bdc63f
- 出典データセット
- uspto-grants-2001_04
- 特許番号
- US06211215B1
関連ノート
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