化工社化工社 化学情報印刷レポート · 研究参考用
1-[4-(4-Hydroxyphenyl)butyl]imidazole → HCID 22009673、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-[4-(4-Hydroxyphenyl)butyl]imidazole | HCID 22009664 | — |
| 反応物 | 2-(5-Bromo-4-methyl-2-thienyl)-4-chloromethyloxazole | HCID 22009708 | — |
| 生成物 | HCID 22009673 | HCID 22009673 | 93% |
反応手順
In substantially the same manner as in Working Example 72, 1-[4-(4-hydroxyphenyl)butyl]imidazole was allowed to react with 2-(5-bromo-4-methyl-2-thienyl)-4-chloromethyloxazole to give 2-(5-bromo-4-methyl-2-thienyl)-4-[4-[4-(1-imidazolyl)butyl]phenoxymethyl]oxazole. The yield was 93%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 85-86° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06211215B1 |
| 出典データセット | uspto-grants-2001_04 |
| ORD ID | ord-76f27ee4d07343f491fa5c7a573e9adc |
| 出典メモ | uspto-grants-2001_04 |