化工社化工社 化学情報印刷レポート · 研究参考用
N,N'-Dimethylurea → Acetamide, 2-cyano-N-methyl-N-[(methylamino)carbonyl]-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N,N'-Dimethylurea | HCID 7293 | — |
| 反応物 | Urea, N,N'-bis(phenylmethyl)- | HCID 72889 | — |
| 反応物 | AcOH AcOAc | HCID 21895370 | — |
| 生成物 | Acetamide, 2-cyano-N-methyl-N-[(methylamino)carbonyl]- | HCID 170228 | 90% |
反応手順
Cyanoacetyldimethylurea is prepared in analogy to Example 1. Instead of dibenzylurea, dimethylurea is employed. The product is worked up by stripping off the acetic anhydride/acetic acid mixture on a rotary evaporator under reduced pressure. The residue obtained in this way is recrystallized from water.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06211270B1 |
| 出典データセット | uspto-grants-2001_04 |
| ORD ID | ord-231981908a694978b11ad2fdec7dfee1 |
| 出典メモ | uspto-grants-2001_04 |