3-(Methylthio)phenylacetic acid → N-[(3-methylthiophenyl)acetyl]alanine Iso-butyl Ester

HRID 322670ノート

反応式

HRID 322670 の反応式
[CH3:1][S:2][C:3]1[CH:4]=[C:5]([CH2:9][C:10]([OH:12])=O)[CH:6]=[CH:7][CH:8]=1.[CH2:13]([O:17][C:18](=[O:22])[C@H:19]([CH3:21])[NH2:20])[CH:14]([CH3:16])[CH3:15]>>[CH2:13]([O:17][C:18](=[O:22])[C@H:19]([CH3:21])[NH:20][C:10](=[O:12])[CH2:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([S:2][CH3:1])[CH:4]=1)[CH:14]([CH3:16])[CH3:15]

参加物

3

反応物 2

HCID 27374613-(Methylthio)phenylacetic acidHCID 137435562-methylpropyl (2S)-2-aminopropanoate

生成物 1

HCID 15481777N-[(3-methylthiophenyl)acetyl]alanine Iso-butyl Ester

実験手順

Following General Procedure I′ above, and using 3-methylthiophenylacetic acid (CAS# 18698-73-2) and alanine iso-butyl ester (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tIc on silica gel and purification was by filtration as described in the general procedure.

後処理

  1. customprepared

出典と根拠

ORDレコード
ord-c6edf2a0e127495fb06db37e95615d50
出典データセット
uspto-grants-2001_04
特許番号
US06211235B1

反応ノート

読み込み中…