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n-PROPYL NITRATE → 2,4-Dibenzyloxybenzonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | n-PROPYL NITRATE | HCID 12307 | — |
| 反応物 | Diammonium hydrogen phosphate | HCID 24540 | — |
| 反応物 | 2,4-Bis(benzyloxy)benzaldehyde | HCID 1809080 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 2,4-Dibenzyloxybenzonitrile | HCID 10313604 | 40% |
反応手順
A mixture of 2,4-dibenzyloxybenzaldehyde (1.59 g), diammonium hydrogen phosphate (3.5 g) and n-propyl nitrate (15 mL) in glacial acetic acid (5 mL) is refluxed for 15 hours. The reaction mixture is evaporated to dryness in vacuo and the residue is stirred with water (100 mL). The insoluble material is filtered and dried at 50° C. to yield 2,4-dibenzyloxybenzonitrile as a tan coloured solid (0.6 g, 40%), m.p. 100° C. [Elemental analysis:- C,79.8; H,5.47; N,4.48%. Calculated:- C,80.0; H,5.43; N,4.44%].
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06211234B1 |
| 出典データセット | uspto-grants-2001_04 |
| ORD ID | ord-9831dfc070f94d43ac3683f15f5f4b2f |
| 出典メモ | uspto-grants-2001_04 |