関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Pentane | HCID 8003 | — |
| 反応物 | Carbon tetrabromide | HCID 11205 | — |
| 反応物 | Triphenylphosphine | HCID 11776 | — |
| 反応物 | 2,4-Bis(benzyloxy)benzaldehyde | HCID 1809080 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 1-(2,4-Dibenzyloxyphenyl)-2,2-dibromoethylene | HCID 11798715 | 68.4% |
反応手順
A mixture of triphenylphosphine (15.7 g) and carbon tetrabromide (9.93 g) in dry dichloromethane (100 mL) is cooled to 0° C. and stirred for 30 minutes. A solution of 2,4-dibenzyloxybenzaldehyde (4.76 g) in dichloromethane (30 mL) is added and the solution stirred at 0° C. for 2 hours. The solution is treated with pentane to precipitate triphenylphosphine oxide. The filtrate is evaporated to give 1-(2,4-dibenzyloxyphenyl)-2,2-dibromoethylene as a yellow oil (4.85 g, 67%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06211234B1 |
|---|
| 出典データセット | uspto-grants-2001_04 |
|---|
| ORD ID | ord-1f5077ce98f64c369bc2d8c7b353d101 |
|---|
| 出典メモ | uspto-grants-2001_04 |
|---|
