化工社化工社 化学情報印刷レポート · 研究参考用
Methyl cyanoacetate → methyl (E)-3-(2,4-dibenzyloxyphenyl)-2-cyanoacrylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl cyanoacetate | HCID 7747 | — |
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | 2,4-Bis(benzyloxy)benzaldehyde | HCID 1809080 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | methyl (E)-3-(2,4-dibenzyloxyphenyl)-2-cyanoacrylate | HCID 86756581 | — |
反応手順
A mixture of 2,4-dibenzyloxybenzaldehyde (1 g), methyl cyanoacetate (0.27 mL), piperidine (0.1 mL) and ethanol (30 mL) is stirred at ambient temperature for 20 minutes and the solvent is removed under reduced pressure. The residue is recrystallized from ethanol to give methyl (E)-3-(2,4-dibenzyloxyphenyl)-2-cyanoacrylate as a yellow solid (400 mg).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06211234B1 |
| 出典データセット | uspto-grants-2001_04 |
| ORD ID | ord-c5088d268910443a81fef21ea2bc3c30 |
| 出典メモ | uspto-grants-2001_04 |