4-Bromophenyl isocyanate → HCID 21184636、化合物

HRID 323037

反応式

HRID 323037 の反応式
[OH:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH2:4].[Br:12][C:13]1[CH:18]=[CH:17][C:16]([N:19]=[C:20]=[O:21])=[CH:15][CH:14]=1>>[OH:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH:4][C:20]([NH:19][C:16]1[CH:17]=[CH:18][C:13]([Br:12])=[CH:14][CH:15]=1)=[O:21]

参加物

3

反応物 2

HCID 756094-Bromophenyl isocyanateHCID 49847212-Amino-5-Nitrophenol

生成物 1

HCID 21184636HCID 21184636、化合物収率 37%

実験手順

N-(2-Hydroxy-4-nitrophenyl)-N′-(4-bromo phenyl)urea was prepared from 2-hydroxy 4-nitro aniline (500 mg, 3.24 mmol) and 4-bromo phenyl isocyanate (3.24 mmol) according to the procedure in General Method B. The product was purified by dilution with methylene chloride and precipitation with hexanes. Filtering afforded ihe title compound (0.41 g, 37%). EI-MS m/z 352 (M+H)+

後処理

  1. customThe product was purified by dilution with methylene chloride and precipitation with hexanes
  2. filtrationFiltering

出典と根拠

ORDレコード
ord-d5d4105144a141d9b99b55418998a29b
出典データセット
uspto-grants-2001_04
特許番号
US06211373B1

関連ノート

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