2-Anilino4-(2-formyl-1-isopropylimidazol-5-yl)pyrimidine → 2-Anilino-4-[2-(pyridin-4-ylcarbonyl)-1-isopropylimidazol-5-yl]pyrimidine

関与物質

反応手順

The title compound was prepared by the procedure of Example 6 from 2-anilino-4-(2-formyl-1 -isopropylimidazol-5-yl)pyrimidine (Example 10) and N-methoxy-N-methyl 4-pyridinecarboxamide (Method 7). NMR (CDCl3): 1.55-1.75 (m, 10H), 5.56-5.72 (sept, 1H), 6.98 (d, 1H), 7.10 (t, 1H), 7.20 (br s, 1H), 7.30-7.40 (m, 2H), 7.55 (s, 1H) (7.60 (d, 2H), 7.90-7.94 (m, 2H), 8.51 (d, 1H), 8.78-8.82 (m, 2 H); m/z 385.

情報源と証拠