Hydrochloric Acid → (1-(2-(trifluoromethoxy)ethyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amine hydrochloric acid salt
反応式
[F:1][C:2]([F:30])([F:29])[O:3][CH2:4][CH2:5][N:6]1[C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=2[N:8]=[C:7]1[NH:15][CH:16]1[CH2:21][CH2:20][N:19](C(OC(C)(C)C)=O)[CH2:18][CH2:17]1.[ClH:31]>O1CCOCC1>[ClH:31].[F:30][C:2]([F:1])([F:29])[O:3][CH2:4][CH2:5][N:6]1[C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=2[N:8]=[C:7]1[NH:15][CH:16]1[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]1参加物
4
実験手順
Combine (1-(2-(trifluoromethoxy)ethyl)-1H-benzimidazol-2-yl)(1-(t-butoxycarbonyl)piperidin-4-yl)amine and a solution of hydrochloric acid in dioxane (10 mL, 4 M). After 1 hour, evaporate in vacuo to give the title compound.