Phenylacetic Acid → HCID 70228322、化合物
反応式
[C:1]1([CH2:7][C:8]([OH:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:11][CH:12]([C:19]#[C:20][Si:21]([CH3:24])([CH3:23])[CH3:22])[CH2:13][C:14]([O:16][CH2:17][CH3:18])=[O:15]>>[C:1]1([CH2:7][C:8]([OH:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:11][CH:12]([C:19]#[C:20][Si:21]([CH3:24])([CH3:22])[CH3:23])[CH2:13][C:14]([O:16][CH2:17][CH3:18])=[O:15]参加物
3
実験手順
Preparation phenyl acetic acid salt of racemic ethyl 3-amino-5-(trimethylsilyl)-4-pentynoate. Racemic ethyl 3-amino-5-(trimethylsilyl)-4-pentynoate (67 g) was reacted with 39 g of phenylacetic acid. The product was filtered and washed with hexane and dried in a vacuum oven to give 100 g the desired racemic ethyl 3-amino-5-(trimethylsilyl)-4-pentynoate phenyl acetic acid salt.
後処理
- filtrationThe product was filtered
- washwashed with hexane
- customdried in a vacuum oven