Phenol, 4-(trans-4-propylcyclohexyl)- → HCID 178447904、化合物

関与物質

反応条件

反応手順

A soluton of 500 g of 4-(4-n-propylcyclohexyl)-phenol in 5 l of toluene is hydrogenated at a hydrogen pressure of 5 bar and 120° C. in the presence of 50 g of palladium on activated carbon (5% by weight). The reaction mixture is filtered and freed from water by azeotropic distillation. It is then treated with 110 g of pyridine sulfone (pyridine-sulfur trioxide complex), stirred at 50° C. for 1 hour and filtered using basic alumina. After removal of the solvent, 433 g (86% yield) of the trans-4-(4-n-propylcyclohexyl)cyclohexanone remain as a colourless solidified melt having a purity of 99.5% (GC).

情報源と証拠