化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → Acridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Isatin | HCID 7054 | — |
| 反応物 | 3-Chloroacridinecarboxylic acid | HCID 18006790 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Potassium Hydroxide | HCID 14797 | — |
| 生成物 | Acridine | HCID 9215 | — |
反応手順
3-Chloroacridinecarboxylic acid. The isatin product from step (a) was refluxed in 300 mL of 10% KOH solution in water for ca. 48 h. The solution was cooled and acidified to pH 2-3 with HCl. The yellow solid was suction filtered after 1 h and then washed with water. The solid was air-dried over night, washed with CH2Cl2 and then air-dried yielding 23.76 g of the acridine acid. 1H NMR (DMSO-d6) 8 7.72-8.30 (m, 7H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06218137B1 |
| 出典データセット | uspto-grants-2001_04 |
| ORD ID | ord-6023d4cdbeb04b639c5e35e39eab9645 |
| 出典メモ | uspto-grants-2001_04 |