Hydrochloric Acid → Acridine
反応式
[NH:1]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:4](=O)[C:2]1=O.Cl>[OH-].[K+].O>[CH:4]1[CH:2]=[C:2]2[CH:4]=[C:6]3[C:11](=[N:1][C:8]2=[CH:7][CH:6]=1)[CH:10]=[CH:9][CH:8]=[CH:7]3参加物
5
実験手順
The isatin product was refluxed in 110 mL of 10% KOH solution in water over night. The dark green mixture was cooled and acidified with 400 mL of 1:1 ice/5 M HCl. The solid was washed with water and air-dried yielding the acridine acid. 1H NMR (DMSO-d6) δ 7.81-7.94 (m, 4H), 8.31-8.36 (m, 2H).
後処理
- temperatureThe dark green mixture was cooled
- washThe solid was washed with water
- customair-dried
出典と根拠
- ORDレコード
- ord-899d982ee2cd4e77a93c91ee5f87c025
- 出典データセット
- uspto-grants-2001_04
- 特許番号
- US06218137B1
反応ノート
読み込み中…