Hydrochloric Acid → Acridine

HRID 324170

反応式

HRID 324170 の反応式
[NH:1]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:4](=O)[C:2]1=O.Cl>[OH-].[K+].O>[CH:4]1[CH:2]=[C:2]2[CH:4]=[C:6]3[C:11](=[N:1][C:8]2=[CH:7][CH:6]=1)[CH:10]=[CH:9][CH:8]=[CH:7]3

参加物

5

反応物 2

HCID 313Hydrochloric AcidHCID 7054Isatin

生成物 1

HCID 9215Acridine

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 14797Potassium Hydroxide溶媒

実験手順

The isatin product was refluxed in 110 mL of 10% KOH solution in water over night. The dark green mixture was cooled and acidified with 400 mL of 1:1 ice/5 M HCl. The solid was washed with water and air-dried yielding the acridine acid. 1H NMR (DMSO-d6) δ 7.81-7.94 (m, 4H), 8.31-8.36 (m, 2H).

後処理

  1. temperatureThe dark green mixture was cooled
  2. washThe solid was washed with water
  3. customair-dried

出典と根拠

ORDレコード
ord-899d982ee2cd4e77a93c91ee5f87c025
出典データセット
uspto-grants-2001_04
特許番号
US06218137B1

関連ノート

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