Lithium hydroxide, monohydrate → CID 53416564

HRID 324406ノート

反応式

HRID 324406 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][CH:11]=[CH:12][C:13]([O:15]C)=[O:14])[CH:6]=[CH:7][CH:8]=1.O.[OH-].[Li+]>CO.O>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][CH:11]=[CH:12][C:13]([OH:15])=[O:14])[CH:6]=[CH:7][CH:8]=1

参加物

5

反応物 2

HCID 168937Lithium hydroxide, monohydrateHCID 71366468Methyl 5-(3-methoxyphenyl)penta-2,4-dienoate

生成物 1

HCID 53416564CID 53416564

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 962Water溶媒

実験手順

A mixture of the product from step (i) (53.2 g) and lithium hydroxide monohydrate (52 g) in methanol (250 ml) and water (100 ml) was stirred at room temperature for 24 hours and partitioned between ethyl acetate and 2M HCl. The organic phase was washed with brine, dried (MgSO4), and evaporated under reduced pressure to afford an orange oil.

後処理

  1. custompartitioned between ethyl acetate and 2M HCl
  2. washThe organic phase was washed with brine
  3. dry with materialdried (MgSO4)
  4. customevaporated under reduced pressure
  5. customto afford an orange oil

出典と根拠

ORDレコード
ord-b14c1bd298ba46eb80b47bab84b4d6c7
出典データセット
uspto-grants-2001_04
特許番号
US06218376B1

反応ノート

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