化工社化工社 化学情報印刷レポート · 研究参考用
2-Acetylnaphthalene → (S)-(-)-1-(2-Naphthyl)ethanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Acetylnaphthalene | HCID 7122 | — |
| 反応物 | alpha-Methylnaphthalene-2-methanol | HCID 98243 | — |
| 反応物 | (R)-(+)-1-(2-Naphthyl)ethanol | HCID 6976569 | — |
| 生成物 | (S)-(-)-1-(2-Naphthyl)ethanol | HCID 6976568 | 50% |
反応手順
As shown here, the biochemical conversion reaction of immobilized green pea protein for the substrate 1-(2-naphthyl)ethanol (201 mg) requires 4 days by going through bioconversion to 2-acetonaphthone accompanying sterically selective oxidation of (R)-1-(2-naphthyl)ethanol to obtain 100 mg of (S)-1-(2-naphthyl)ethanol at a yield of 50% at an optical purity of 99% e.e. or higher (see FIG. 1).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06218581B1 |
| 出典データセット | uspto-grants-2001_04 |
| ORD ID | ord-7b35a6765154448fa7d62659ae817dc6 |
| 出典メモ | uspto-grants-2001_04 |