4'-Methoxyacetophenone → (1R)-1-(4-methoxyphenyl)ethan-1-ol

関与物質

反応手順

As shown here, the biochemical conversion reaction of immobilized buckwheat protein for the substrate (±)-1-(4-methoxyphenyl)ethanol (200 mg) requires 6 days by going through bioconversion to 4-methoxyacetophenone accompanying sterically selective oxidation of (S)-1-(4-methoxyphenyl)ethanol to obtain 112 mg of (R)-1-(4-methoxyphenyl)ethanol at a yield of 46%. Optical purity was obtained at 99% e.e.

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