化工社化工社 化学情報印刷レポート · 研究参考用
3-Thiophen-2-ylprop-2-enoic acid → 3-(2-Thienyl)propanoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Thiophen-2-ylprop-2-enoic acid | HCID 92868 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 3-(2-Thienyl)propanoic acid | HCID 703169 | 77.6% |
反応手順
To a solution of 3-(2-thienyl)acrylic acid (7 g) in ethanol was added 5% palladium on carbon and the mixture was hydrogenated at 50 psi in a Parr apparatus. The catalyst was filtered off and the solvent was removed by evaporation to yield the title compound (5.5 g) as an oil. Electrospray MS m/z 155 [M−H]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06218538B1 |
| 出典データセット | uspto-grants-2001_04 |
| ORD ID | ord-1d78723a0ed54ea097bab6291d5bbe04 |
| 出典メモ | uspto-grants-2001_04 |