化工社化工社 化学情報印刷レポート · 研究参考用
alpha-Tocopherol → alpha-Tocopherol 4-aminobenzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | alpha-Tocopherol | HCID 14985 | — |
| 反応物 | Benzoyl chloride, 4-amino- | HCID 177720 | — |
| 触媒 | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | alpha-Tocopherol 4-aminobenzoate | HCID 86756642 | 68% |
反応手順
The reaction of alpha-tocopherol with 4-aminobenzoic acid chloride was carried out in the same manner with Example I, except that 10 mol % of 4-(dimethylamino)pyridine was added together with pyridine. This reaction was confirmed to proceed in a similar pattern to that of Example I as measured by thin layer chromatography. The remaining processes of Example I were repeated to produce alpha-tocopherol 4-aminobenzoate (0.61 g, yield 68%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06222051B1 |
| 出典データセット | uspto-grants-2001_04 |
| ORD ID | ord-84a2330b294a46d5b04e558ac57f83de |
| 出典メモ | uspto-grants-2001_04 |