Hydrochloric Acid → S-methyl-L-cysteine ethylamide hydrochloride

HRID 325325ノート

反応式

HRID 325325 の反応式
[ClH:1].[CH2:2]([NH:4][C:5](=[O:18])[C@H:6]([CH2:15][S:16][CH3:17])[NH:7]C(OCCCC)=O)[CH3:3]>C(OCC)(=O)C>[ClH:1].[CH2:2]([NH:4][C:5](=[O:18])[C@H:6]([CH2:15][S:16][CH3:17])[NH2:7])[CH3:3]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 57312465S-methyl-N-butyloxycarbonyl-L-cysteine ethylamide

生成物 1

HCID 86739336S-methyl-L-cysteine ethylamide hydrochloride収率 94%

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒2 回

実験手順

To 60 ml of ice-cooled 16% solution of hydrogen chloride in ethyl acetate was added dropwise a solution of 3.93 g (15 mmole) of S-methyl-N-butyloxycarbonyl-L-cysteine ethylamide in 60 ml of ethyl acetate over 20 minutes. After stirring for 2 hours, the reaction mixture was concentrated in vacuo and the residual oil was treated with ethyl ether to give 2.8 g (94% yield) of S-methyl-L-cysteine ethylamide hydrochloride as powder.

後処理

  1. concentrationthe reaction mixture was concentrated in vacuo
  2. additionthe residual oil was treated with ethyl ether

出典と根拠

ORDレコード
ord-f4ecd067f5454a37ad5c0649b6210e4c
出典データセット
uspto-grants-1984_04
特許番号
US04440788

反応ノート

読み込み中…