Maleic Anhydride → 3a,4,7,7a-Tetrahydro-4,7-epoxyisobenzofuran-1,3-dione

HRID 325439

反応式

HRID 325439 の反応式
[C:1]1(=[O:7])[O:6][C:4](=[O:5])[CH:3]=[CH:2]1>O1C=CC=C1>[CH:4]12[O:6][CH:1]([CH:3]3[C:4](=[O:5])[O:6][C:1](=[O:7])[CH:2]31)[CH:2]=[CH:3]2

参加物

3

反応物 1

HCID 7923Maleic Anhydride

生成物 1

HCID 984843a,4,7,7a-Tetrahydro-4,7-epoxyisobenzofuran-1,3-dione収率 170%

試薬・触媒・溶媒 1

HCID 8029Furan溶媒

実験手順

Maleic anhydride (50 g) and furan (150 ml) were heated under reflux for 1 hour, and then the excess of furan was distilled off. The residue was recrystallised from chloroform, yielding 72 g of 7-oxabicyclo [2.2.1]hept-2-ene-5,6-dicarboxylic acid anhydride (m.pt. 110° C., decomp.). This anhydride (40 g) and 30.75 g of 2-hydroxyethyl acrylate were heated in 250 ml of toluene at 100° C. for 3 hours, and then the toluene was distilled off under reduced pressure, leaving the desired compound as a viscous liquid.

後処理

  1. temperatureunder reflux for 1 hour
  2. distillationthe excess of furan was distilled off
  3. customThe residue was recrystallised from chloroform

出典と根拠

ORDレコード
ord-ee81ebf605ea41feba46e0e8b08cc2a7
出典データセット
uspto-grants-1984_04
特許番号
US04440850

関連ノート

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