Timonacic → 3-[3-(4-Pentadecenylamino)benzoyl]-4-carboxythiazolidine

HRID 325570

反応式

HRID 325570 の反応式
[CH2:1]([NH:16][C:17]1[CH:18]=[C:19]([CH:32]=[CH:33][CH:34]=1)[C:20]([N:22]1[CH:26]([C:27]([O:29]CC)=[O:28])[CH2:25][S:24][CH2:23]1)=[O:21])[CH2:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15].S1CC(C(O)=O)NC1>C(=O)(O)[O-].[Na+].CC(C)=O>[CH2:1]([NH:16][C:17]1[CH:18]=[C:19]([CH:32]=[CH:33][CH:34]=1)[C:20]([N:22]1[CH:26]([C:27]([OH:29])=[O:28])[CH2:25][S:24][CH2:23]1)=[O:21])[CH2:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]

参加物

4

反応物 2

HCID 9934TimonacicHCID 538623083-[3-(4-Pentadecenylamino)benzoyl]-4-carboethoxythiazolidine

生成物 1

HCID 537972693-[3-(4-Pentadecenylamino)benzoyl]-4-carboxythiazolidine

試薬・触媒・溶媒 1

HCID 86737261Acetone sodium bicarbonate溶媒

実験手順

By means of the alkaline hydrolysis method of Example 2 the ethyl ester of Example 548 is converted to the subject carboxylic acid. This acid is also prepared using the procedure of Example 548 except that the acylation of the thiazolidine-4-carboxylic acid is carried out in aqueous acetone sodium bicarbonate solution.

後処理

  1. customThis acid is also prepared

出典と根拠

ORDレコード
ord-df868f938c0f45f6a856aa523a785110
出典データセット
uspto-grants-1984_04
特許番号
US04440940

関連ノート

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