Methylhydrazine → 1-Methyl-N5-[3-[3-[(dimethylamino)methyl]phenoxy]propyl]-1H-1,2,4-triazole-3,5-diamine
反応式
CSC(=N)[N:4]([C:19]#[N:20])[CH2:5][CH2:6][CH2:7][O:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([CH2:15][N:16]([CH3:18])[CH3:17])[CH:10]=1.[CH3:22][NH:23][NH2:24].[CH3:25][N:26](C)C=O>>[CH3:22][N:23]1[C:19]([NH:4][CH2:5][CH2:6][CH2:7][O:8][C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([CH2:15][N:16]([CH3:17])[CH3:18])[CH:10]=2)=[N:20][C:25]([NH2:26])=[N:24]1参加物
4
実験手順
N-Cyano-N-[3-[3-[(dimethylamino)methyl]phenoxy]propyl]-carbamimidothioic acid methyl ester (1.5 g) and N-methylhydrazine (1.2 g) in dimethylformamide (15 ml) were heated at 40° for 24 hours. The solvent was removed, and the residue was triturated with ether to yield the title compound as a white solid (1.0 g) m.p. 95°-96.5°.
後処理
- customThe solvent was removed
- customthe residue was triturated with ether
出典と根拠
- ORDレコード
- ord-7cf01d215f5e4e0ba9a9b32cbb727d42
- 出典データセット
- uspto-grants-1984_04
- 特許番号
- US04442110
反応ノート
読み込み中…