関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Pyridine | HCID 1049 | — |
| 反応物 | Acetyl chloride | HCID 6367 | — |
| 反応物 | 4-Nitro-2,3-dihydro-1H-inden-1-OL | HCID 13102456 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 4-Nitro-1-indanyl acetate | HCID 13102457 | 100.9% |
反応手順
A stirred solution of 40.0 g (0.51 mole) of acetyl chloride and 43.9 g (0.56 mole) of pyridine in 100 mL of toluene was cooled to 5° C., and a solution of 83.0 g (0.46 mole) of 4-nitro-1-indanol in 30 mL of toluene was added dropwise. Upon complete addition, the reaction mixture was stirred at 5° C. for 10 minutes, then was allowed to warm to ambient temperature and was stirred for 16 hours. The reaction mixture was filtered, and the filtrate concentrated under reduced pressure to give 102.7 g of 4-nitro-1-indanyl acetate as an oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04442296 |
|---|
| 出典データセット | uspto-grants-1984_04 |
|---|
| ORD ID | ord-4cc013002cce473d981f6e1411362719 |
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| 出典メモ | uspto-grants-1984_04 |
|---|
