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3-Amino-5-methyl-4H-1,2,4-triazole → 2-Methyl-7-(3-pyridyl)[1,2,4]triazolo[1,5-a]pyrimidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Amino-5-methyl-4H-1,2,4-triazole | HCID 234610 | — |
| 反応物 | 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one | HCID 567033 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 2-Methyl-7-(3-pyridyl)[1,2,4]triazolo[1,5-a]pyrimidine | HCID 13309047 | 40.3% |
反応手順
A reaction mixture of 0.98 g of 3-amino-5-methyl-1,2,4-triazole and 1.76 g of 3-dimethylamino-1-(3-pyridyl)-2-propene-1-one in 25 ml of glacial acetic acid was refluxed for six hours. The procedure was continued as for Example 1 to give 0.85 g of the product of the Example as colorless crystals, mp 244°-245° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04444774 |
| 出典データセット | uspto-grants-1984_04 |
| ORD ID | ord-bad9db7dc83c474b9c6285756bf3a620 |
| 出典メモ | uspto-grants-1984_04 |