Ethylamine → 6-[1-(Cyclohexylmethyl)-4-phenyl-1H-imidazol-5-yl]-thieno[2,3-d]pyrimidin-4-amine
反応式
[CH2:1]([N:3]1[C:7]([C:8]2[S:18][C:11]3[N:12]=[CH:13][N:14]=[C:15](SC)[C:10]=3[CH:9]=2)=[C:6]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[N:5]=[CH:4]1)[CH3:2].C([NH2:27])C.[CH:28]1(CN)[CH2:33][CH2:32]C[CH2:30][CH2:29]1>>[CH:2]1([CH2:1][N:3]2[C:7]([C:8]3[S:18][C:11]4[N:12]=[CH:13][N:14]=[C:15]([NH2:27])[C:10]=4[CH:9]=3)=[C:6]([C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=3)[N:5]=[CH:4]2)[CH2:32][CH2:33][CH2:28][CH2:29][CH2:30]1参加物
4
実験手順
The title compound was prepared using the general method of Example 56 and Intermediate 70 but replacing ethylamine with the cyclohexylmethylamine. Solid (20 mg, 19%);
出典と根拠
- ORDレコード
- ord-f2721244d3434d35b11815968024f82c
- 出典データセット